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Associations between lutein, zeaxanthin

The leading cause of vision loss among older people is the age-related macular degeneration(AMD) which causes the death and dysfunction of the photoreceptors found in the macula. Researchers found that xanthophylls: lutein and zeaxanthin, the only carotenoids found in both the macula and lens of the human eye play important functions in filtering blue light and as antioxidants and may help prevent degeneration of photoreceptors. There are evidences that

show the relation of age, gender, iris color, smoking, dietary intake, body mass index and the presence of existing diseases to macular pigment optical density (MPOD) and AMD. Studies on subjects with AMD and without AMD showed increases in MPOD and serum concentrations with high dietary intakes of lutein and zeaxanthin. Only few studies that measured the effects of retinal function has been documented. However, the effective dietary doses of lutein and zeaxanthin either as whole food or supplemental form has not yet been determined.

Carpentier, et. al. (2009) stated that although lutein and zeaxanthin have been proven to be beneficial to eye health, more evidence to support that they may lower the risk of developing AMD or may delay the progression to late-stage AMD is needed. Associations between lutein, zeaxanthin 3 Reference Carpentier, S. Knaus, M. and Suh, M. (2009). Associations between Lutein, Zeaxanthin and Age-Related Macular Degeneration: An Overview. Critical Reviews in Food Science and Nutrition, 2009 Apr; 49 (2): 313-26.

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